DPCstruct | MC36121

Metacluster Properties and Pfam Annotations

Number of structural domains226
Mean domain length (aa)245 ± 60 aa
Standard deviation of domain lengths60.44
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score86.83
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.65
Pfam Score40.24
Assigned Pfam label(s) CL0116- PF03441- CL0179- PF20375- PF14249

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A810EA22 51-272 EYGQSQLAFEETPDPHFRLQLIDQTFQAELLFHPQKPLANIDEDGKLNKLRYHSLPRNQVLGQIEQGGMTETVTGEGWFDHQWGRDY…
A0A6J6UVR8 14-183 HYLGEHHLDQPGRYVGSIVLRGEQIAVDSYGFRDRSWGPRSQFGVGLSSSSAQHGGYSYATASASDAFHTITMDFGSGCNNIHGYLL…
A0A6A6Z8L0 7-166 None
Q64C98 60-329 None
A0A661GSQ8 2-121 None
A0A1D2S6D4 8-310 None
A0A1C6BV23 224-403 None
A0A838UJU2 9-201 None
O45136 96-421 None
A0A1W9QGR0 17-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.