DPCstruct | MC3612

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)155 ± 28 aa
Standard deviation of domain lengths27.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.99
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V9HZX2 3-151 ISTGFGMRVLFVGLALALAVVMAQETPQEKKFFEVKITKDEIYSYNGIKFAGDYTSWESPSGQLALGRTEGGVTILVILGAGTFKIE…
A0A2V9UXV8 17-137 SYQQLRNLALGGETVGVSNLTIHRDAGTFHLRSGIVCFVVPVAGKVTGAVFVGDGNFVLDPALPSENASLKMLTRESEFSETFTQAV…
A0A7W0NTS9 1-185 None
A0A7V0UCQ4 1-162 None
A0A3E0P482 32-216 None
A0A2V8XR54 2-129 None
A0A2V9JLB6 1-188 None
A0A2V8UPJ3 151-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.