DPCstruct | MC36071

Metacluster Properties and Pfam Annotations

Number of structural domains253
Mean domain length (aa)88 ± 15 aa
Standard deviation of domain lengths14.84
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.26
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)39.18
Pfam Score94.78
Assigned Pfam label(s) PF01201- CL0110- CL0260- CL0376- PF01486

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A833VVM5 8-88 GETKKVKRGRVKLARIEDKTSRQVRFSKRRSGLFKKASELAVLCDAEVALLVFSPAGRLFEFSSCSWYFTLLPCAKQERAY
A0A183IZY2 4-67 EVTFTKRKFGLMKKAYELSVLCDCEIGLIIFNSSNKLFQYASTNMDAVLLKYTEYNEPHESRTN
A0A368QVA5 29-157 None
A0A6P8CFF3 50-141 None
A0A1S8W1X3 148-255 None
A0A7N2L6I2 3-126 None
A0A0E0GJU3 9-106 None
D7UBC1 1-78 None
R9P9A4 1-82 None
A0A445JJY2 1-63 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.