DPCstruct | MC36025

Metacluster Properties and Pfam Annotations

Number of structural domains2141
Mean domain length (aa)254 ± 44 aa
Standard deviation of domain lengths43.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.14
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.32
Mean intra-cluster sequence similarity (%)9.30
Pfam Score70.04
Assigned Pfam label(s) PF18951- PF14742- CL0194- CL0177- CL0103

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V5YDM1 21-277 DSGNIRQAGEGRYILENEYLEVELNALKGGGIENIRYKPANTSLTGGSQGISFEDRIYRQRREGSNRLVETEYFISRPYSVKILKDT…
A0A641W7B2 45-282 PTIARPWGMNFWTPQTGKMGDGWQYVYTANKIRGFKQTHQPSPWINDYGQFSIMPMVGKPEFDEEKRASWFGHKGEEATPYYYKVYL…
A0A7J9RKU6 710-1043 None
A0A4Q2XEJ4 4-258 None
A0A450SDR9 261-577 None
A0A3N5WI94 385-621 None
A0A0S8AJR1 440-640 None
A0A0B5HXB5 131-312 None
A0A7V9GGC0 93-356 None
A0A3R8NS16 137-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.