DPCstruct | MC36021

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)103 ± 8 aa
Standard deviation of domain lengths7.58
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score86.93
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)37.38
Pfam Score100.00
Assigned Pfam label(s) PF12423

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4AUR5 2-96 EELYQRFLDGEDSHVTQEDDPFWDPVEVIHLGSAHVWLQSLAYCMKFEEQVEFLNCDGLEEAVLHIHMASCSPTGQAHGEEDVVIDP…
A0A2C9LBM5 68-167 FQNYTEGDPDWNVPKEKDPFWEPVSTPVLIGTSLVYLQPLAYLIDMDESLAVIDWKGKEIGQLLVSLVPCDSKWEPLSDSSYVEDPK…
A0A816RXR4 235-337 None
A0A2H2ITV0 38-146 None
U6K636 29-126 None
A0A1S3J029 151-261 None
A0A448WSP1 22-121 None
A0A4W3IQH6 4-86 None
A0A183RGG0 265-370 None
F6VIA3 82-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.