DPCstruct | MC35989

Metacluster Properties and Pfam Annotations

Number of structural domains57
Mean domain length (aa)242 ± 46 aa
Standard deviation of domain lengths45.58
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.67
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.34
Pfam Score84.16
Assigned Pfam label(s) CL0123- CL0031- CL0166- PF03123- CL0493

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377F4W6 1-185 MQDSIYISLTDHCQFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMHLVSAQMSGNMEDVAGV…
A0A381H917 2-235 PEQLQPILQEIFTRFRIRLTDEGELFLRLYCAVAVRRISEGYPLSEFTTEEVEDNVCFAARDIAAVLQHLADKPLSASEENWLKVHI…
A0A5N1BFI8 1-273 None
A0A645G4P3 7-219 None
A0A6N6XDP6 103-334 None
A0A1S1BP42 14-319 None
D7UWU4 58-245 None
A0A3F3GSM4 4-267 None
A0A7H4SH90 8-194 None
A0A645BR75 57-372 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.