DPCstruct | MC35976

Metacluster Properties and Pfam Annotations

Number of structural domains303
Mean domain length (aa)282 ± 61 aa
Standard deviation of domain lengths60.67
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.20
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.52
Pfam Score99.50
Assigned Pfam label(s) CL0286- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4Y263 7-290 IRFGVEIETPLVRTGNGDRDSIADSLLEELRNVKHLDIDIKWVLEDIVGFEFKSPVFDLGRDWRAQVRKLWETIGVRQSTTPEHFVH…
A0A663LSZ9 171-419 RRIMDMVSNQHPWFGMEQEYTLLGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKIGGTNAEVMPAQWEF…
A0A139LKR3 8-235 None
B1V1K4 89-364 None
A0A4S9V562 2-412 None
A0A0S7ZQI5 2-367 None
A0A4Y8CQS8 1-429 None
A0A1G2I264 80-322 None
A0A496SRY9 159-387 None
A0A194UWA7 335-641 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.