DPCstruct | MC35974

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)108 ± 8 aa
Standard deviation of domain lengths7.65
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.81
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)34.51
Pfam Score100.00
Assigned Pfam label(s) CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V5MSD8 193-304 EKYRLAIDFLRQQLREQPRTSVGGFWHKKVYPHQMWLDGLFMATPFLAQYAVFAKEPAAMDDAVKQLLLVAEKTFDPSTGLYTHAWD…
A0A4Q4XDM1 2-119 LKDWRERTDDEKYKEVARVVREQSDKTPRTATGPRAGSGIATRIYPNQMWLDGMLDGGFFYAKWARLFDADNTTARDDIVLQFDNFE…
A0A4Q5X8S5 548-642 None
A0A0S6W510 633-734 None
Q5B659 396-504 None
A0A194W2Z9 182-294 None
A0A7K0KE11 598-697 None
M2SXV5 113-219 None
A0A2S5ADF3 112-226 None
W4UU83 398-512 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.