DPCstruct | MC35957

Metacluster Properties and Pfam Annotations

Number of structural domains174
Mean domain length (aa)177 ± 26 aa
Standard deviation of domain lengths26.16
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.81
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)16.89
Pfam Score86.45
Assigned Pfam label(s) PF07589- PF13448

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K7YSJ1 24-203 ISIDELNFDQDYWTITDLSTNATGTSLFQIEVEQADYESNFGLYYIDDTSQSVTKFKVFDKSNEPITKVTISFLYDDSDWWITNNYT…
A0A259CD28 335-479 ATTAGGADDQDVVVRLRQNGINDISVMFYEVDDFGGTIAGIAPGQAGYDAAAAARAYLTQDGLSAINGAGYGAYSQTEITGVDAGDY…
A0A2E6QP24 141-348 None
A0A1H8MHK3 1003-1167 None
A0A7G7EN62 76-260 None
A0A521TVM2 78-262 None
A0A521U829 27-219 None
A0A7X6CGM3 120-325 None
A0A368N0K8 68-245 None
A0A1H8W9W4 569-744 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.