DPCstruct | MC3595

Metacluster Properties and Pfam Annotations

Number of structural domains246
Mean domain length (aa)425 ± 92 aa
Standard deviation of domain lengths92.31
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.77
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.42
Pfam Score82.69
Assigned Pfam label(s) PF07324- CL0221- PF13967- CL0416- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2AXU2 75-622 None
H2AYW5 56-655 None
A0A0C9M3A7 339-684 None
A0A7S2QRG7 5-358 None
A0A7S0A5Z9 5-308 None
A0A812ZVW8 180-606 None
A0A7S2K1L6 279-772 None
A0A7S2BGZ4 1-433 None
A0A7M5WZY0 388-888 None
A0A0V0QFY8 32-577 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.