DPCstruct | MC3595

Metacluster Properties and Pfam Annotations

Number of structural domains246
Mean domain length (aa)425 ± 92 aa
Standard deviation of domain lengths92.31
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.77
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.42
Pfam Score82.69
Assigned Pfam label(s) PF07324- CL0221- PF13967- CL0416- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2CS07 430-911 None
K1R6C7 702-1079 None
A0A6A1QE06 264-773 None
A0A813H9C2 4-267 None
W4H916 370-862 None
W4HAX8 2-564 None
A8Y0C9 2-405 None
G0R4V6 98-654 None
A0A6A6Y9S3 586-1081 None
A0A2T0FPH1 103-615 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.