DPCstruct | MC3595

Metacluster Properties and Pfam Annotations

Number of structural domains246
Mean domain length (aa)425 ± 92 aa
Standard deviation of domain lengths92.31
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.77
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.42
Pfam Score82.69
Assigned Pfam label(s) PF07324- CL0221- PF13967- CL0416- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3XKI6 36-489 YAYWLLVPAAAGLAYGAYAVAAGDPGESEGVNYYQVAFVTVVILWTVLYKTHWDQESALIAVAWGTHGFEEEEADRPQFRGWPEEPR…
A0A7S1R4A7 65-457 DTAFIVFETRGGRDCALTASKKKALGLWGAVLKLQATTHEPESVFWEEFAVSQTEHLLREVKAFVYTVTCSILWTVILYLPYAHYMA…
W4GHV2 346-839 None
A0A6A5UN88 254-655 None
H0EVI8 122-552 None
A0A7S4RV32 586-1054 None
M2T989 82-475 None
A0A7S1XUZ3 89-464 None
A0A7S3ZRY5 2-432 None
A0A7S4A2Z5 587-1088 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.