DPCstruct | MC35916

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)134 ± 16 aa
Standard deviation of domain lengths15.65
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.64
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)36.41
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A080ZHR7 28-153 VAIEADSCECKSTPRPCIFLHGLGNPNEKAELQDTPKLTKEKFGDIGDHAPCCTTVKYAVINTVDVGWRNDTLQQKFCDFSLSMSET…
T0PTR6 278-396 IESASCGCKMAKKPCLFVHGAGNYFNASLSDIFLFEWGLAHLHAPCCSSIKFAHFETWFRGWEEESIHNQFCDAALQVSNAKPNSTS…
A0A397APR1 210-341 None
A0A3F2RMM8 133-264 None
A0A1Z4KDZ5 4-149 None
W4GZZ5 3-123 None
K3WWG0 97-252 None
G4ZCP7 102-242 None
D0NVD0 69-225 None
D0NP22 20-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.