DPCstruct | MC35907

Metacluster Properties and Pfam Annotations

Number of structural domains156
Mean domain length (aa)275 ± 53 aa
Standard deviation of domain lengths52.93
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.80
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)17.25
Pfam Score100.00
Assigned Pfam label(s) CL0472

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V2AP06 11-247 TMDLLAIALAPGFAIILFILYRDKFDREPAVVLLVSFFFGMLSTVPAIAIEDAVGYFNLSGIQGTVISAFLGVALVEELVKFIPLRL…
A0A1Y1S0Q1 5-225 PIIMAIIPSLVLVLLFMRFDRRRPEPRGEILRAFVLGVFSTIPVLVLEILVDAFFSPWFTNPLYLAVLEAFVVAALCEEGIKLMVVR…
A0A7Y4ZSI3 74-319 None
A0A2G2KDD2 44-299 None
A0A537ZIX4 33-330 None
A0A1H2UMM4 164-463 None
A0A358SUD0 32-346 None
A0A518AJ22 94-292 None
A0A838RMR1 44-302 None
A0A2E9IMY5 115-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.