DPCstruct | MC35880

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)206 ± 37 aa
Standard deviation of domain lengths36.79
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.67
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.64
Pfam Score99.36
Assigned Pfam label(s) PF03169- CL0523

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397TR03 53-278 NSEDNSVNELISAAANVNDDPSLPCLTFRFWVLSTFFTVLGAAISVFYYFRSNYLNYSIFFVILLSYTAGKWMEKMLPTRRFRIKNW…
A0A4D9C3Q9 23-234 ENSPVEQVALTVPPTDDPSLPVVTFRMWILGAAACVLLSFLNQFFWYRREPLSISSISAQIAVVPLGHLLAAALTRRVFFPGRRWEF…
E3KXH7 61-234 None
A0A444C9B9 386-547 None
A0A0G4NL58 111-352 None
A0A6A2XSJ1 21-180 None
M0ZW46 2-217 None
A0A177U433 81-294 None
A0A7D8UQZ9 55-249 None
A0A1S8VCU1 22-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.