DPCstruct | MC35869

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)144 ± 23 aa
Standard deviation of domain lengths23.41
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.70
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)14.28
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A374W5E1 1-124 MPLSKARVEDYPGSSYITFISGIWTRINFSKADFKEKQSGNGELIEQTFEATITNTDSDNEAILQAVVSELGFLRIDYTNGGIKVAG…
A0A3N2KQ60 4-103 LGSEDDAVAVPGSVKVSTTSDNGIIKKKITFERSDVSDSTADALEGYKVSRLIATYVDESGKRRVAGSPDWPLSLDYSIGDGVFSVT…
A0A3R8UEX7 3-148 None
G8R3S3 50-209 None
A0A496P2M7 6-140 None
A0A519TM08 136-298 None
A0A4Q8RTX9 82-229 None
A0A7Y0YPL3 1-96 None
A0A3D5AAD6 3-138 None
A0A316RDL5 3-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.