DPCstruct | MC35852

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)127 ± 17 aa
Standard deviation of domain lengths16.91
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score87.80
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y4B800 7-117 VIPEHASVANAVGAVVGNVSASVTAQIRPDPVSAENFCVITQETSAVFSDYDESMAYAREQIEKTAEELLIQKGGKPPFSTSFSQNK…
A0A832TDS3 98-232 MVVGTGYLAQFLVPRIARHSGASFTIPPHAECANAVGVAVSRVTLTLHARFDSGRGAVVFNGEPQELRTLGDDEAVLDRCRAEVKQR…
A0A1V4YHH6 148-287 None
A0A7K4A8A7 84-226 None
A0A7X9HE79 272-405 None
A0A396R2I1 3-94 None
A0A1V5E5K8 109-255 None
A0A1V5NK74 127-259 None
A0A6G2JU45 3-96 None
A0A7X6UA37 305-428 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.