DPCstruct | MC35837

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)159 ± 21 aa
Standard deviation of domain lengths20.77
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.20
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)41.33
Pfam Score92.54
Assigned Pfam label(s) PF00521- CL0413- PF16898

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A817CBT0 290-442 TAKEAKEYFSNMDRHRIIFKYDSIKDDLAIQLAFNSALSDDRKDWIKWHTEDINQRREQNLPADYLYKKDTKQINFNDFINKELVLF…
A0A7R9JH90 1-142 MSRHRIKFKYAGPQDDANITMAFSKKCIDDRKVWLTNWMEDTKRRHEMGLPEQYLYEKDTKQVNYSDFVNKELVLFSNMDNERSIPS…
A0A816VFU0 8-140 None
A0A0R3Q3X3 364-547 None
A0A250XKH7 499-673 None
A0A453PC30 68-219 None
A0A453PC23 280-462 None
A0A6P8WQY5 583-766 None
A0A817FQN4 1-129 None
A0A820PZH8 1-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.