DPCstruct | MC35836

Metacluster Properties and Pfam Annotations

Number of structural domains3
Mean domain length (aa)287 ± 2 aa
Standard deviation of domain lengths1.70
Length coefficient of variation0.01
Mean AlphaFold2 pLDDT confidence score76.44
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.36
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)24.78
Pfam Score83.33
Assigned Pfam label(s) PF08880- PF07529

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T0FBT2 78-365 TSPLEHTELQVPITALKLLTRNVDLPEALQAQLIQLAGEPVDEPATKQHENGSTKRLTFKERSARLGLEPEIGTAAGGGAEMVIRSR…
E3M5Q4 89-373 QQITTAQLNQLKAQVSAYRLLARNEQVPESLISEAVMLRPKVTTLLPDPYEYAGEGENGEKLPYDLMKIFNLHQIRCNRPSTVPPPN…
A0A2Z6SI78 70-358 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.