DPCstruct | MC35826

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)285 ± 66 aa
Standard deviation of domain lengths65.78
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.29
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)19.01
Pfam Score100.00
Assigned Pfam label(s) CL0179

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K2QWX1 4-246 DHFVVDPLTGRVLERRLGDKRIAVRSIPGGGTRTLATSNGGAAACLTDKQAAELAALGHRVEGHFGSPQDIEWAIAGDGHFWLTQSR…
A0A824U0J5 2-331 KNSNAGAFLSLANIKADSKDELLKALYEVANSMPSKSDEILVQPMLENITLCGVGFSVDKDNFSPYFCLQYDENGSNSSITDGSSKS…
A0A7R9Q5T6 7-259 None
A0A1V5BU58 35-288 None
A0A1F6CKH0 3-331 None
A0A0K2RID4 7-240 None
A0A135VT78 189-541 None
A0A4V2AL41 1-443 None
F9EFE7 211-479 None
A0A4R3MR73 16-414 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.