DPCstruct | MC35815

Metacluster Properties and Pfam Annotations

Number of structural domains127
Mean domain length (aa)116 ± 23 aa
Standard deviation of domain lengths23.26
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.57
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.50
Pfam Score97.97
Assigned Pfam label(s) CL0159- PF04148- CL0267- CL0303

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G3I6W8 33-148 PQGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRA…
A0A3M2SVA0 3-74 IHPTCKVGDLANKQILDLNAALSEMRIENDLRRKVLDDIRRLRESGSNRGRRHALGLPVHGQSTRTNHKTAV
A0A212CM12 5-95 None
A0A1I8F228 17-153 None
A0A396HN26 1-70 None
A0A3P6DF52 1-70 None
A0A6P5MYG1 28-112 None
A0A6M3X264 6-113 None
A0A1E5UNM4 1-87 None
A0A519D8Z9 9-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.