DPCstruct | MC35812

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)318 ± 68 aa
Standard deviation of domain lengths68.04
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.62
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)32.34
Pfam Score90.24
Assigned Pfam label(s) PF08337- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2I224 2-218 VTEIYLTRLLMMKGTLAKFITDLLESIFSSRNVPPCIKYMFDFMDEQAREHAINDPEVVHAWKSNALPLRFWVNLIKNPHFLFDIQK…
G3HWR4 12-365 SDLKDSAGEPLYKLFKAIKHQVERGPVDAVQKAAKYTLNDTGLLGDDVEYSPLTVSVIIQDEGVEAIPVKVLNCDTISQVKEKIIEQ…
A0A3B3QIQ7 183-387 None
A0A183MQA4 706-961 None
H3A2E1 39-411 None
A0A7M7HNM1 15-279 None
A0A816UWJ5 51-548 None
A0A2B4SHF4 410-771 None
A0A5J5CEK7 316-700 None
S4RGT4 1-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.