DPCstruct | MC35780

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)131 ± 32 aa
Standard deviation of domain lengths32.12
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score79.60
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)66.13
Pfam Score100.00
Assigned Pfam label(s) PF16422

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J5YAX6 9-129 STRLSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTSYLDFVEKDKEPGGEKTNNGIHYKLQLLFSNGVRTEQDLY…
A0A452FYX1 32-147 GVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLID…
A0A498NB65 1-78 None
A0A139WNP7 247-407 None
T1EJB1 1-84 None
T1EJY6 1-92 None
A0A194PSR7 145-305 None
A0A1A9XXC4 1-116 None
A0A1B0C1K3 2-94 None
A0A3P4PIZ8 27-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.