DPCstruct | MC35769

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)205 ± 36 aa
Standard deviation of domain lengths36.16
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.70
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)41.09
Pfam Score99.22
Assigned Pfam label(s) CL0036- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8HFZ7 2-204 EAKEGQTWTPESWKALPIKQQPEYEDNEALAKALAKVQKLPPIVHQMEIEKLKTYLAQACEGKMFLLQGGDCAERFDECCQETIEKK…
A0A800FKN9 4-156 WTKDSWKDFNIKHIPEYKDQNELNETLDRLKTFPPLVFAGECKNLKSELAKAVEGKAFLVQGGDCAESFKEFNANNIRDTFRVILQM…
A0A3D9LUQ9 345-513 None
M7Z6H5 2-190 None
M7YGY0 1-98 None
A0A3Q0FJ36 120-373 None
H6SRE3 440-690 None
R9NVV2 4-236 None
A0A841BQH0 7-190 None
A0A2S4VP28 3-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.