DPCstruct | MC35756

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)134 ± 17 aa
Standard deviation of domain lengths17.36
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.76
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)22.48
Pfam Score98.89
Assigned Pfam label(s) CL0123- CL0288

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183HM00 5-143 IHRILETSLFDLEQIVTVQYLSRHADISIDDAKDELAEFLMQNKNRTELHAVYVLSGKLKVPDFGSDNTSDTAITPKYRTQLVRDCD…
A0A803YPC9 6-128 YLENIDEFVTDQNRIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVTYLVAGNLTQNGHTCHKVAVVREDKLEAVKSKL…
F4Q9X7 12-165 None
A0A7R9KT84 4-150 None
A0A6I9Q1Z3 2-150 None
A0A4Q4VS81 1-121 None
A0A5A7VHS8 393-541 None
A0A0N4ZSZ4 2-137 None
A0A2C5YYI5 1-112 None
K3WL94 8-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.