DPCstruct | MC3575

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)300 ± 72 aa
Standard deviation of domain lengths71.90
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score80.13
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)25.92
Pfam Score97.22
Assigned Pfam label(s) PF02470- CL0649

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1R1LYR3 3-377 DHQDIPEAVVTPKERLSIIWLLPLVAVAIGAWLFYKSQAEADIPVLIHFPTGQGLVAGKTEVRYQGIPIGLVEEFELDTDLDGVVAK…
A0A2N7QMY7 11-262 TGLFIVLGFAALGYLATQTTSVANTSRGPSYIVEAHFANIGQLKERAPVKVAGVRIGQVQSIVLDPGKETADVKLSIDKRYDQIPDN…
A0A0B8NYA0 3-285 None
A0A2N9YA63 8-330 None
A0A3S4JAN9 456-767 None
A0A4U9HCJ7 41-225 None
M1PHR4 86-434 None
A0A4R1IFA7 22-290 None
A0A142WPX8 227-492 None
A0A7Y2KX90 130-481 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.