DPCstruct | MC35738

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)132 ± 31 aa
Standard deviation of domain lengths30.90
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.05
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)58.34
Pfam Score100.00
Assigned Pfam label(s) CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183WV43 5-103 EEYASTPVHTLDHLEYFALLQSLSLDYRLTDPFVSLGCLSPIQRHLLDEYCTRYGIRECQRHLAMLINLLNKIENGMTIDPDLIHIS…
A0A183HDC6 34-143 QGFADKASKHGMDELIQADPINFDHDHLFCKLQSLTLDFQLNEPICSLGWFSPGQVFVLDEYCARYMVRGCHRHVSFLNDLLNKTDE…
A0A3P7WSE6 612-750 None
A0A3P7L9R4 4-113 None
A0A7E4RQ26 539-648 None
A0A132A995 78-186 None
A0A183RU94 66-181 None
A0A7J7KTE2 727-842 None
A0A0S7FIK5 60-214 None
A0A060X1P4 2-100 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.