DPCstruct | MC35735

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)124 ± 11 aa
Standard deviation of domain lengths10.56
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score82.60
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)34.66
Pfam Score100.00
Assigned Pfam label(s) PF08638

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K1K4M5 21-144 GKAESHEPSLEQLESELPLVMDDQLPLGELVSRLAQAVYAELVEMAETMPSMSDAARKRYVADWVIRTKRQVVKLYAIAKWSRDAAV…
A0A183HC69 1-123 MDDEEYMKPMLPTVPEKCGPPVIPLGHLIEFAVQQIFHELTVLSELLPKKLDSDRKISIVQFAHSTRVLFIKLLAVVKWVKSSKKFE…
A0A1X7TVP4 4-105 None
A0A819P3K7 193-309 None
P0CB66 47-179 None
A0A6J0EFA2 25-143 None
A0A1Y2GIS7 38-177 None
A0A817D8W5 5-121 None
A0A0C2N6G2 4-106 None
A0A1I7RJG6 17-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.