DPCstruct | MC35464

Metacluster Properties and Pfam Annotations

Number of structural domains118
Mean domain length (aa)307 ± 85 aa
Standard deviation of domain lengths84.64
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score84.31
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.73
Pfam Score80.93
Assigned Pfam label(s) PF00542- PF04561- CL0410- PF04563- PF04565

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K3NKU4 15-376 TKFQIDSFNNFVNVDLKRTVDVNGFITVKLSTDDENQFSLRLLDARIGRDDITRTPLECRSCDLTYTAPILVDIEYSQGRRDEILTR…
W1DQD2 5-214 PQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIY…
A0A2A2KTH8 1-246 None
A0A1V5JVL6 4-327 None
Q8HTL6 162-693 None
A0A1P8BFS9 46-403 None
A0A1I8F8V7 161-416 None
A0A345HH11 52-292 None
A0A820V5C5 18-293 None
A0A1D6DWV2 57-438 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.