DPCstruct | MC35456

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)148 ± 15 aa
Standard deviation of domain lengths15.48
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.63
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q6TH44 3-148 LQEMKFYCPLEISRWDDDEYNEISPNEASAYESEINYFISDFNLPEEKERGLMHWYNRGNSVDQKVFSAFMSVEENDEELVGVVTAS…
A0A3A9EE56 16-136 VKLTFYCPLVGQLDDGECDEYIDIGSGFLAAYQDQIEQAIANEQVPEMGDMTQYLGDDPGVAEKLMSAVWIVEDMDGKLFGRIDCHL…
A0A1V5XD07 232-379 None
A0A845RK54 73-224 None
A0A645C801 16-180 None
A0A1Y4HAF4 60-214 None
A0A3R6L9X0 7-157 None
A0A1M6I5T4 4-180 None
A0A6I7GJ83 85-230 None
A0A0W1JGX2 97-259 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.