DPCstruct | MC35451

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)465 ± 100 aa
Standard deviation of domain lengths100.26
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.07
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)39.21
Pfam Score73.29
Assigned Pfam label(s) CL0004- CL0126- PF00066

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3AAN1 2-407 FAGLFDNCSHSLSDKGWTLGIQSSDHLGRKDACFFFTMRTDRARKATTVLGHSHYLPNVWVHVAATYDGHWMTLYVDSVQVGRSGGQ…
A0A812DJL5 25-432 PRVFFSYRTLSTYSRCFSATVPDALLTFNIFYFFSFLGLFDMCHQDHKAKGWNIGIRTYEEGQEEGARIYFSLETDRANSPSVLMSD…
F1Q5Q4 55-527 None
A0A6A5F4D5 229-683 None
A0A401SDD0 6-528 None
A0A6J0VA35 7-415 None
A0A0B2UZL6 1-554 None
A0A0H5S603 5-305 None
A0A498MT86 22-485 None
A0A0V0Y441 264-703 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.