DPCstruct | MC35448

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)98 ± 16 aa
Standard deviation of domain lengths15.85
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.71
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)35.75
Pfam Score100.00
Assigned Pfam label(s) PF07347

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812DF70 1-85 MAPRRGVTPIVAIIRNWFLGLKFQNPLRYEDAYSKRTQPPPNLPVGPSHKLSSNYYYTRDPRREVLPPELAYHPLKAIAPGDDKE
A0A1B0CIC7 1-78 MASSARRDISPFLRNLRNFLLGRSHTNALRFEDGLAARTQPPPDVPGGPAHKLSANYYVNRDARREVQPPMDVTRVLL
A0A0M3HS56 1-104 None
A0A2P8Y2A6 2-75 None
A0A498LW32 43-162 None
A0A482X692 41-129 None
A0A131Y1K7 1-86 None
A0A1A9UU65 3-102 None
B4J318 1-129 None
A0A194R1S5 1-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.