DPCstruct | MC35435

Metacluster Properties and Pfam Annotations

Number of structural domains592
Mean domain length (aa)65 ± 9 aa
Standard deviation of domain lengths8.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.23
Assigned Pfam label(s) PF00057- CL0123- PF00095- PF01826- CL0692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M3R8X0 927-977 None
A0A819WAF9 456-527 None
P00993 4-61 None
A0A183DZP6 481-545 None
B3LY99 33-95 None
B2C6G1 86-160 None
K1S707 500-561 None
A0A1X7UAX0 20-84 None
A0A4W5RU84 521-581 None
Q6ZNI4 89-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.