DPCstruct | MC35435

Metacluster Properties and Pfam Annotations

Number of structural domains592
Mean domain length (aa)65 ± 9 aa
Standard deviation of domain lengths8.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.23
Assigned Pfam label(s) PF00057- CL0123- PF00095- PF01826- CL0692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A553Q8D0 489-547 None
A0A7R9I198 790-845 None
R7V4K6 864-922 None
Q4LDX2 8-79 None
R7VFH6 59-119 None
A0A315V8K6 136-198 None
A0A1I8A9Z9 47-108 None
A0A1I8AGB8 147-208 None
A0A1I8ALK0 466-543 None
A0A1I8ANJ5 74-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.