DPCstruct | MC35435

Metacluster Properties and Pfam Annotations

Number of structural domains592
Mean domain length (aa)65 ± 9 aa
Standard deviation of domain lengths8.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.12
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.13
Pfam Score97.23
Assigned Pfam label(s) PF00057- CL0123- PF00095- PF01826- CL0692

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A674JZG3 5-69 SPPESCAAPRLTGPCRAAFPRWYYDPAARACRQFIYGGCKGNKNNYLREEQCLRQCSGAAGGAEG
P82968 142-194 DACSLKKVVGPCRGAFRRYYFDSVSGKCEEFVYGGCGGNDNNFKTLDACQKRC
A0A6J1WSX0 5-61 None
A0A4W4FH88 132-202 None
A0A7E5WNF2 27-100 None
A0A7E5WQ36 34-98 None
A0A7E5X0I8 530-598 None
A0A2C9JLS0 60-124 None
A0A3Q0IM45 11-80 None
A0A0K0EE57 203-261 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.