DPCstruct | MC35413

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)109 ± 14 aa
Standard deviation of domain lengths14.45
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.32
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.98
Pfam Score100.00
Assigned Pfam label(s) CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G2R526 14-117 LPPIENEILEGAPSSTWRDLRNPKLRRFPRHGAEITWLDFLGHGIAGLVFKVTIGGGDPVALKIFWRARRPKPRPRPNDDGFIQDEW…
A0A2H3S2V8 1-123 MEEDISRLRRAEEIRVLEKAQTRAATVAFCDDILISSPPSCPAADFKRPRLRRCLFDPTTIDWSHSTRVGGGLDGYIWKVWFGADGP…
A0A175VZS6 1-116 None
A0A2H4SBN6 1-116 None
A0A2H4S8A2 16-151 None
A0A4Z0Y2N3 15-118 None
S3D1J2 17-157 None
A0A2S7Y9Y2 18-127 None
A0A2A9PIU7 2-100 None
A0A2A9PI13 3-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.