DPCstruct | MC35412

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)215 ± 42 aa
Standard deviation of domain lengths41.83
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.86
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)27.67
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B7E1Q3 111-375 DIPGFEVVEDVALGTFSFAKYLMWKDLVDREAKLRESPLVRHLIDRDGRIEQDSDKLPRVEDLDTQIEPAELFTPLPADSSQLRAVI…
A0A3F3KDQ5 4-221 SLSGGITEIPYINDILQNSIKDSQVKPQNIFQVLDADSSQQVVIEAAKRGDSFVVQGPPGTGKSQTIVNMITELIGAGKSVLLVAAK…
A0A7X3NWN7 280-477 None
A0A7K2E6H5 264-505 None
U2Z4Q1 633-843 None
H6RIG2 1-239 None
A0A7I9Y451 275-517 None
F8C8M0 400-593 None
A0A7S0M0E6 254-392 None
A0A6G3VP99 76-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.