DPCstruct | MC354

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)159 ± 30 aa
Standard deviation of domain lengths30.43
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.44
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.90
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X0UUQ9 5-140 LAEINKVEQALASAFDIIDILELRTKAKAVEVVALAEGFADVAQNAKIFQLKAERKAGSWLDGNIQHGGNSKSRHVTLDDIEISKSQ…
A0A158B087 24-176 YRNAVTALEQATKIDECQSWADKAMALASYARQSRDDTLCKMAVRIQNRASRRCGELLAQVPRNPGGSPTHKATRVGVNPSSPSSEF…
A0A518L717 1-132 None
G2J872 36-283 None
A0A1I7NF53 2-193 None
A0A0F9JZ39 6-179 None
A0A7C9K7K6 2-122 None
Q3SSC6 3-149 None
A0A380WK67 8-170 None
A0A2U3IE81 28-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.