DPCstruct | MC35391

Metacluster Properties and Pfam Annotations

Number of structural domains625
Mean domain length (aa)257 ± 61 aa
Standard deviation of domain lengths61.14
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.16
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)15.15
Pfam Score84.26
Assigned Pfam label(s) CL0046- PF04675- CL0179- CL0680- CL0329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0E3WYM4 14-172 TDTVCVEEKMNGFNVRAILFDGKITAITRGGYVCPYSTEKAGQLLNIDFFNDHPELVLHGEMVGPDNPYVPKKIYDDVDSIDFYVFD…
A0A329D150 5-245 IEPQLATLVERHPTAGDWSYEIKFDGYRMLARLENGIVNLITRNGHDWTTRMPRLREALETLPADTAWIDGEAVVLDAAGKPDFNAL…
A0A177WII1 460-667 None
A0A257MDK1 20-240 None
A0A2W1BSD6 2-272 None
A0A158N7X3 89-282 None
A0A2U1QNX7 789-1030 None
A0A0S4JRM1 89-357 None
A0A1E4ZIW4 78-422 None
A0A3D4H826 32-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.