DPCstruct | MC35386

Metacluster Properties and Pfam Annotations

Number of structural domains571
Mean domain length (aa)165 ± 36 aa
Standard deviation of domain lengths35.95
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.25
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)17.96
Pfam Score97.96
Assigned Pfam label(s) CL0010- PF18980- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C4F212 2-120 None
A0A2H3IBP4 350-576 None
A0A7M3Q6S0 6-132 None
A0A2A2LEY9 231-347 None
F6HI26 108-328 None
A0A2U1KIW1 364-573 None
A0A1D2M9R2 171-339 None
A0A1D2MJK3 99-270 None
A0A6G0UZH3 185-341 None
A0A0C2W2X3 778-987 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.