DPCstruct | MC35386

Metacluster Properties and Pfam Annotations

Number of structural domains571
Mean domain length (aa)165 ± 36 aa
Standard deviation of domain lengths35.95
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.25
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)17.96
Pfam Score97.96
Assigned Pfam label(s) CL0010- PF18980- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M2Q457 1-127 MPYTLGFGLVNNGFSIFAPKGRKLPITFEGEYFNAFDNQSDIVDTIYKGEGQKTNEEGMELVTKVTIEGLPPGLKAGEFKIIDKTTV…
A0A2P6PIK8 23-170 QSINPDEAVAHGAAVHAAVLSGKGGGKLQDFTLLDATPVSLGVEVGADFMGIVIPRNTKVPVVKNCSMTTRYDNQVNVIFAIYEGES…
A0A6A6LLA6 255-394 None
M2RYS7 94-251 None
D4KW47 2-134 None
A0A0F7S3H2 687-889 None
A0A2N9IQY2 73-184 None
A0A3P6H2K0 8-142 None
A0A1Y2HQI5 603-804 None
B0E8N6 2-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.