DPCstruct | MC35306

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)74 ± 5 aa
Standard deviation of domain lengths4.57
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.27
Mean fraction of residues predicted as intrinsically disordered0.14
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)71.68
Pfam Score100.00
Assigned Pfam label(s) PF02445

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6H5KRE0 210-280 SESEIGCSLAEAAERKAYEAWLRKASATANSMHVVYINTSLVTKALSHSLVPTITCTSSNVLHTVLQAFAQ
A6GBP5 120-198 SESAIGCSLAESAEALAYGAWLDQAANTPNSLHVVYINTSLRTKARAHHKVPTITCTSSNVVATVLQTFAQEPEAHVWF
A0A426ZBH0 1-71 None
A0A383W510 312-378 None
A0A6I9RPR4 225-302 None
A0A0D9XYP5 204-281 None
A0A7J0GAN0 291-359 None
A0A0D6QRI5 72-138 None
A0A2P6TPP4 337-412 None
A0A0E0J955 375-452 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.