DPCstruct | MC35254

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)197 ± 29 aa
Standard deviation of domain lengths29.47
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.25
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)16.63
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A837ISQ7 3-167 YTGDANNFSVDYIVSYSPYGLNDGAISGHVPYATFVKKTYDSESAAANDVPYQSSDSSSGLPTVDLGHGISGVMDSGAGQRYLQWNE…
A0A6N8I1W6 2-193 LPTNIPVEKNRYLTATTVSQTLNYKVNFYETTKTAKINSPSVSKGTLIATLEGIKYKGTASAKASISDYVQINAADYDEFVDLGHRI…
A0A2T2X3H9 302-521 None
A0A7X9N4H9 89-310 None
A0A2K8N6G1 122-343 None
D5WT54 124-340 None
A0A0P9GQC9 214-386 None
A0A2T2XEW5 6-148 None
A0A2T2WXR8 86-300 None
A0A2T2WJC2 194-438 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.