DPCstruct | MC35185

Metacluster Properties and Pfam Annotations

Number of structural domains5770
Mean domain length (aa)212 ± 50 aa
Standard deviation of domain lengths50.25
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.43
Pfam Score95.69
Assigned Pfam label(s) CL0442- CL0288- CL0219- PF01221- CL0174

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7PUU8 3-198 None
A0A2S6WPU6 282-528 None
A0A347Q3Z2 492-683 None
A0A2H3CDZ4 270-422 None
H6SS55 828-1059 None
A0A7C2JY19 34-270 None
A0A226F6P8 273-435 None
A0A226EUS0 39-315 None
A0A226ET32 149-414 None
A0A226ELA1 45-255 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.