DPCstruct | MC35185

Metacluster Properties and Pfam Annotations

Number of structural domains5770
Mean domain length (aa)212 ± 50 aa
Standard deviation of domain lengths50.25
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.43
Pfam Score95.69
Assigned Pfam label(s) CL0442- CL0288- CL0219- PF01221- CL0174

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E5A189 65-326 None
E4ZK42 70-301 None
A0A6I9ZCN5 294-492 None
A0A010SN10 11-176 None
A0A010SAM1 3-196 None
A0A010S086 7-258 None
A0A2C6AL46 238-493 None
A0A0A2WL32 351-564 None
A0A0A2WEF6 1-162 None
A0A401L8F3 1-283 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.