DPCstruct | MC35185

Metacluster Properties and Pfam Annotations

Number of structural domains5770
Mean domain length (aa)212 ± 50 aa
Standard deviation of domain lengths50.25
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.43
Pfam Score95.69
Assigned Pfam label(s) CL0442- CL0288- CL0219- PF01221- CL0174

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4C1WBC8 72-315 None
A0A845MYI4 1-198 None
A0A0V0UIE8 185-439 None
A0A5J4X4N8 27-264 None
A0A6B1MUF6 10-215 None
A0A6B1MTQ3 273-500 None
A0A6B1MSU1 2-177 None
A0A6B1MRW1 172-336 None
A0A6B1MRR4 90-235 None
A0A6B1MRC7 41-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.