DPCstruct | MC35185

Metacluster Properties and Pfam Annotations

Number of structural domains5770
Mean domain length (aa)212 ± 50 aa
Standard deviation of domain lengths50.25
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.43
Pfam Score95.69
Assigned Pfam label(s) CL0442- CL0288- CL0219- PF01221- CL0174

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0Z8J444 5-219 LITGASGGLVQEMVPLLKDDFLILLGRDVEKIEQLYAYHEKKAVFDVDIRDEEALTAFFDQVDSQFGQIDILVNNAGYAIYDDFETF…
A0A843ZFK1 2-149 LTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPEDWRGKVSVRQLDYFNQESMVEAFKGMDTVVFIPSIIHPSFKRIPEVENLVY…
A0A1I2KBL7 3-144 None
A0A171JXL7 2-159 None
A0A7R9KKP0 40-284 None
A0A7R9L5A7 3-194 None
A0A7R9KXL3 311-497 None
A0A7R9KQV6 74-225 None
A0A7R9KP27 5-221 None
A0A7R9KMW0 4-246 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.