DPCstruct | MC351

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)168 ± 13 aa
Standard deviation of domain lengths13.34
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score87.80
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2C752 17-170 QPPGFRFDPPLTKGSTVKNLSAFHLLQSSLIRSHDSLLCCQLLRTLQTIWEKDPTNFFLLEWTVQTMRQLSACVQQKPASVQKLFFS…
A0A1B0D248 81-233 IASLCMCGYTELRPNLNQSGSLFQMQGFTMPQTSSRGTCIRNVHAFQVLQTIFLKSNSTPLCCNILDAISSVYHSDNANYFILESQN…
T1GN58 75-256 None
H3A743 352-537 None
W6V355 187-357 None
H3DGI6 224-401 None
A0A1I7XJY6 113-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.