DPCstruct | MC35054

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)129 ± 19 aa
Standard deviation of domain lengths19.07
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.59
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)40.18
Pfam Score98.65
Assigned Pfam label(s) CL0110- CL0270

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D2SG19 115-259 KMEIIPNPKEVNGIKVLQLETAAGAAIRFFDHAIGINVPRSRFLPVKATSDLLLVQSDLYTLVDGFVIRNKDRANPTNPSIELGPEF…
A0A7J8WKB6 20-142 FENPKFFDRAIGINVPRARYLPLRTTADLFLYPCDIYTLVGYVFNRKSKANSLDPVVEFGSEFFKPTDFLSRFKTMPSIIELDSLKV…
A0A7S2I2V0 350-459 None
A0A7S4L862 493-616 None
A0A3E2CS28 7-122 None
A0A3P7DYZ2 2-100 None
A0A7C4ABG6 129-282 None
A0A2K1IK49 351-470 None
A0A0R3T9M6 15-145 None
A0A498NFB1 677-821 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.