DPCstruct | MC35011

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)130 ± 17 aa
Standard deviation of domain lengths16.67
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.56
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)30.80
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C9YM10 4-137 CYKLFCEQFPDMYKQILAMYKDTVVLGKADKTVAQHQHLFHNTSKRLVQLFNSVAKCHAFEGAFLLAGSVVNQDGDLGYMHMTPGAE…
A0A4Y7RJV5 173-280 YQAYIARHPTNFQSLLETFAETCDIEKLFGTTVGQRKAEFKKFTTIVSTLCERFYKRQGFEVAVMGVGNIVNADGNLQFCYETPGVE…
A0A2R6NWM4 556-669 None
F8PZD4 89-228 None
F8PI09 33-177 None
F8NZ09 63-189 None
S7R6M1 123-257 None
A0A0C9YG41 64-176 None
A0A0C9XUH3 3-125 None
A0A165Z1R0 252-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.